Question explored with the scientific record
Conversation so far
- 1 If the dog has yperparathyroidism would he still be doing so much better after prednisone alone and What is standard treatment for hyper parathyoidism in dogs
- 2 How can we tell primary vs secondary hyperparathyroidism?
- 3 How successful in dogs is surgery primary hyperparathyroidism ie what is the odds of cure
- 4 Is surgery for dogs parathyroid common in dogs primary hyperparathyroidism
- 5 What is the cure rate after parathyroidectomy in dogs?
Answered on this page ↓
What is the cure rate after parathyroidectomy in dogs?
The short version: the retrieved evidence is entirely about human parathyroidectomy, so it cannot answer the cure rate in dogs.
None of the 41 records in this retrieval report outcomes for parathyroidectomy in dogs. The human data shows cure rates of 94% to 99% depending on technique and patient group [2][3][4][7][8], but that tells you nothing reliable about canine surgery. Dogs have different parathyroid anatomy, different disease patterns, and different surgical risks. Applying human cure rates to a dog would be guessing.
The retrieval also missed the most important veterinary question: what counts as "cure" in a dog. In humans, cure means normal calcium and PTH at six months or more [5]. In dogs, the same biochemical standard would apply, but this retrieval contains no veterinary study defining or measuring it.
What the human evidence does show is that cure rates vary with disease type. Double adenomas cured 98% of the time [1]. Multiple endocrine neoplasia patients cured only 76% to 92% depending on pathology [6]. A dog with a single adenoma would likely do better than one with hyperplasia, but no record here supports that for dogs specifically.
My call: the evidence does not answer the cure rate after parathyroidectomy in dogs. A veterinary case series with biochemical follow-up would be needed.
Confidence: not clear from this evidence.
Sources used 8
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Intraoperative Parathyroid Hormone Assay in Patients With Primary Hyperparathyroidism and Double Adenoma
A retrospective study evaluating intraoperative parathyroid hormone (IOPTH) monitoring in patients with primary hyperparathyroidism due to double adenomas, demonstrating that IOPTH reliably predicts cure in 98% of such cases and supports selective, limited neck exploration even …
DOI: 10.1001/archoto.2009.192 -
Primary hyperparathyroidism: Referral patterns and outcomes of surgery
A 15-year retrospective audit of 33 patients with primary hyperparathyroidism undergoing parathyroidectomy at North Shore Hospital, Auckland, detailing referral patterns, presentation, surgical outcomes, and pathology, with a high cure rate and relatively few complications.
DOI: 10.1046/j.1445-2197.2002.02343.x -
Parathyroidectomy in a district general hospital: Outcomes and evolution in the era of minimally invasive surgery
This study evaluates outcomes of bilateral neck exploration (BNE) and the uptake/outcomes of minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism in a district general hospital, finding high cure rates comparable to larger centres, with limited MIP uptake l…
DOI: 10.1016/j.ijsu.2012.05.021 -
Secondary hyperparathyroidism is an expected consequence of parathyroidectomy for primary hyperparathyroidism: A prospective study
Prospective analysis of 78 consecutive primary hyperparathyroidism patients undergoing parathyroidectomy shows immediate postoperative declines in PTH and calcium, a 98.7% surgical cure rate, with about 70% experiencing transient hypoparathyroidism and about 12% developing trans…
DOI: 10.1067/msy.1998.92004 -
The Definitive Management of Primary Hyperparathyroidism
Evidence-based guidelines from the American Association of Endocrine Surgeons outlining when parathyroidectomy is indicated for primary hyperparathyroidism, preferred preoperative evaluation, imaging and surgical approaches, intraoperative PTH monitoring, autotransplantation, an…
DOI: 10.1001/jama.2017.1620 -
Primary Hyperparathyroidism in Patients With Multiple Endocrine Neoplasia Syndromes
This study evaluates the surgical outcomes of 45 patients with primary hyperparathyroidism associated with multiple endocrine neoplasia syndromes, revealing a high cure rate but significant risks of postoperative complications.
DOI: 10.1001/archsurg.1983.01390050017003 -
Outpatient parathyroidectomy: a new paradigm from a nursing perspective
This study reviews the evolution of nursing assessment and management for patients with primary hyperparathyroidism, highlighting the shift towards outpatient care and the role of minimally invasive parathyroidectomy as a definitive treatment.
DOI: 10.1097/01.cco.0000149605.21474.55 -
Unilateral Versus Bilateral Neck Exploration for Primary Hyperparathyroidism
This prospective randomized controlled trial compared unilateral versus bilateral neck exploration for primary hyperparathyroidism, finding similar cure rates but less early hypocalcemia and shorter operative time with unilateral exploration in cases of solitary adenoma.
DOI: 10.1097/00000658-200211000-00001