How can I check if any aHSCT MS trial is recruiting in Melbourne/Sydney?

The short version: the trial registries are the only honest answer, and no record here names a Melbourne or Sydney aHSCT trial.

You check recruitment in three places, and you check all three because each one misses what the others catch. The Australian New Zealand Clinical Trials Registry (ANZCTR) is the primary register for trials run in Australia, so search it for "multiple sclerosis" plus "haematopoietic" or "stem cell" and filter by recruiting status and by state. ClinicalTrials.gov carries many Australian sites as secondary locations, so search it for aHSCT in MS and read the "Locations" tab for Melbourne or Sydney. Then confirm on the hospital's own page, because a registry entry can lag months behind a trial that has closed or not yet opened.

What the records do give you is the bar a legitimate site should clear. Guidance for neurologists says aHSCT for MS belongs inside properly regulated clinical studies, at a center with JACIE accreditation (a formal transplant-laboratory accreditation), MS experience, and outcomes reported to a transplant registry [1]. Treatment-related death with modern regimens is estimated at 2 to 3 in 100 for myeloablative conditioning [1], and registry data show it falling below 1 in 100 in recent years [2]. That is the risk you are weighing against a real benefit: in the MIST randomized trial, disability progression at 5 years was about 10 in 100 with aHSCT versus about 75 in 100 on standard drugs [2].

A clinic offering aHSCT for MS with no trial number and no registry entry is selling an unproven product, not running a trial.

My call: use ANZCTR first, then ClinicalTrials.gov, then the hospital's own page, and treat any site that fails the accreditation and registry-reporting bar as a red flag [1]. Confidence: moderate on the method, low on whether any such trial is currently recruiting in either city.