Question explored with the scientific record
Conversation so far
- 1 Stage 0 melanoma in a mole vs not in mole
- 2 Stage 0 melanoma in a mole vs not in mole life expectancy difference
- 3 Stage 0 melanoma life expectancy difference
Answered on this page ↓
Stage 0 melanoma life expectancy difference
The short version: stage 0 melanoma is treated by removal, and the records here don't track life expectancy by whether it started in a mole. The number that matters is how often it turns out to be invasive.
The closest survival data in this retrieval is for melanoma in situ treated with Mohs surgery versus wide local excision: 5-year overall survival was 92% with Mohs and 94% with wide excision, and recurrence was low in both [1]. That is the honest anchor for stage 0 overall, not a mole-versus-skin split.
| Group | 5-year survival | Recurrence |
|---|---|---|
| Mohs surgery | 92% [1] | 1.8% [1] |
| Wide local excision | 94% [1] | 5.7% [1] |
The mole-origin question isn't answered by these records. The earlier thickness and stage-share figures came from a study not in this block, so I'm not re-citing them. What this retrieval does show is that stage 0 survival is high regardless of surgical technique [1], and that the real risk is upstaging at excision, which the prior turn put at 23% across reviewed studies. That figure is not in this block either, so treat it as carried over, not re-verified.
My call: no life-expectancy difference by mole origin can be stated from this evidence, and the surgical choice doesn't move 5-year survival much [1]. Confidence: low.
Sources used 1
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Outcomes of Melanoma In Situ Treated With Mohs Micrographic Surgery Compared With Wide Local Excision
This study compares the outcomes of melanoma in situ treated with Mohs micrographic surgery versus wide local excision, finding no significant differences in recurrence rates or survival outcomes.
DOI: 10.1001/jamadermatol.2016.6138