Which benign conditions most commonly cause PSMA PET uptake?

The retrieved evidence does not directly answer which benign conditions cause PSMA PET uptake.

The studies here focus on benign prostatic hyperplasia (BPH) as a condition, not on PSMA PET imaging. One study on a ganglioneuroma (a benign nerve tumor) used FDG-PET, not PSMA PET [1]. The rest of the records cover BPH treatments, salivary gland tumors, and other benign diseases, but none of them describe PSMA PET radiotracer behavior.

The previous answer documented several confirmed causes of PSMA PET false positives from a different set of records: pancreatic neuroendocrine tumors, nodular fasciitis, chronic beryllium lung disease, and lung adenocarcinoma. Those are the specific benign and non-prostate conditions that have been published as causing uptake.

This retrieval cannot add to that list. It found no studies testing PSMA PET uptake in any benign condition. The question of which benign conditions are most common causes of false positives remains unanswered by these records.

My call: the evidence here does not identify any benign conditions causing PSMA PET uptake. Confidence: not clear from this retrieval.