who should take 0.6 patch.. does it go by weight

The short version: Nitro-Dur 0.6 is not dosed by body weight. It is a fixed-dose patch, and the right patient is someone with stable angina who has not responded to simpler treatments.

The 0.6 mg/h patch delivers a set amount of nitroglycerin through the skin per hour, regardless of how much you weigh. Dosing is by clinical response and tolerance, not by pounds or kilograms. A 1993 study of Nitro-Dur patches showed that the amount of drug that actually reaches the bloodstream depends on the patch design and surface area, not on body size [1]. The 0.6 mg/h patch is the highest standard strength. Lower strengths (0.1, 0.2, 0.3, 0.4 mg/h) exist for people who need less.

Who should take it? The approved use is for preventing angina attacks in people with documented coronary artery disease. The evidence here shows a real problem: tolerance develops within 24 hours of continuous wear, meaning the patch stops working for its main purpose [1]. A 2015 trial of a similar patch for diabetic nerve pain found that 8 of 30 people dropped out due to headache, nausea, vomiting, dizziness, and skin rash [2]. Some reactions were moderate to severe. So the person who should take it is someone whose angina is not controlled by safer options like beta-blockers or calcium channel blockers, who understands the tolerance issue, and who accepts the side effect risk.

My call: Nitro-Dur 0.6 is not weight-based. It is for adults with stable angina who need a third-line option and can tolerate the side effects. Confidence: high on the dosing question (the evidence is clear on patch design [1]), moderate on the patient selection (the tolerance and dropout data are real but come from small studies [1, 2]).