Question explored with the scientific record
Conversation so far
- 1 What about homeopathic observational study in Cuba to prevent leptospirosis in half of island using a nosode administration + a private exchange
- 2 See this further link https://journals.sagepub.com/doi/abs/10.1177/2156587214525402 + a private exchange
- 3 You should report more clearly this subject. As a hypothesis worth further exploration https://www.medigraphic.com/pdfs/revcubhigepi/chi-2022/chi221c.pdf
Answered on this page ↓
You should report more clearly this subject. As a hypothesis worth further exploration https://www.medigraphic.com/pdfs/revcubhigepi/chi-2022/chi221c.pdf
The short version: the retrieval still contains no direct evidence on homeopathic nosodes for leptospirosis, so the 2010 Cuban study remains the only test, and it is too weak to act on.
The evidence block you provided has nothing on the Spanish paper or the Cuban leptospirosis study. The records cover HPV nosode preparation [13], insect larvae experiments [14], cancer nosode preparation [15], and unrelated topics like bird distributions [25]. None test homeopathic nosodes against leptospirosis in humans.
The 2010 Cuban study is the only direct evidence. It was an uncontrolled observational design: no blinding, no placebo group, no correction for rainfall or other environmental confounders. It has never been replicated in 16 years. The systematic review of non-individualized homeopathy found that none of the 17 trials it analyzed were judged reliable evidence, with 14 at high risk of bias. That pattern fits the Cuban study.
My call: the retrieval provides no evidence to change the assessment. The 2010 study cannot support a population-level intervention. Confidence: low — the evidence base is absent from this retrieval, and the single existing study is too weak to rely on.
Sources used 30
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Food and water security issues in Russia III: food- and waterborne diseases in the Russian Arctic, Siberia and the Far East, 2000–2011
A regional epidemiological analysis of official Russian statistics from 2000–2011 across 18 northern regions (Arctic, Siberia, Far East) showing alarmingly high incidences of infectious and parasitic food- and waterborne diseases relative to national levels, with detailed region…
DOI: 10.3402/ijch.v72i0.21856 -
Systematic review of the prevalence of environmental and host-related risk factors and the zoonotic potential of leptospirosis in domestic dogs in regions impacted by environmental changes
A PRISMA-guided systematic review of 26 observational studies (2000–2024) across 12 countries totaling 13,827 domestic dogs, evaluating Leptospira seroprevalence, serovar distribution, and environmental/host-related risk factors within a One Health framework, highlighting region…
DOI: 10.1186/s12917-025-05023-0 -
Serogroups and genotypes of Leptospira spp. strains from bovine aborted foetuses
This Belgian study characterizes the serogroups and genotypes of Leptospira spp. in bovine aborted fetuses from 2011–2014 using serology (MAT), PCR, and MLST, revealing Grippotyphosa and Australis as the predominant serogroups and identifying L. kirschneri and L. interrogans as …
DOI: 10.1111/tbed.12643 -
Purdue University–Banfield National Companion Animal Surveillance Program for Emerging and Zoonotic Diseases
A national companion animal surveillance program at Purdue University, leveraging Banfield and Antech Diagnostics data, monitors vector-borne and zoonotic diseases in dogs and cats to detect unusual clusters, forecast risks, and inform public health actions.
DOI: 10.1089/VBZ.2006.6.14 -
Leptospirosis in Southern Sea Otters from Central California: Detection of Fatal Infections and Pathologic Findings
Retrospective analysis of southern sea otters in central California identifies Leptospira interrogans serovar Pomona infections, with seven fatal cases showing tubulointerstitial nephritis and high Pomona antibody titers, suggesting Pomona-driven leptospirosis and potential land…
DOI: 10.64898/2026.01.08.698541 -
Mapping And Analysis of Environmental Risk Factors Leptospirosis Incidence Based Geographic Information System (GIS) In Sampang Regency
An environmental GIS-based analysis of the 2013 leptospirosis outbreak in Sampang Regency links higher rainfall, lower elevation, and flooding to clustered human cases (107 cases and 9 deaths), concentrated in Sampang district.
DOI: 10.20473/jkl.v8i1.2015.48-56 -
Ratting out leptospirosis: investigation of a revealing urban case associated with socioeconomic disadvantage in Sydney, Australia
An urban leptospirosis case in Sydney linked to socioeconomic disadvantage and rat-infested housing highlights housing/rodent-control as public-health priorities, while rat testing yielded no Leptospira detections and questions remain about reservoir species.
DOI: 10.33321/cdi.2026.50.029 -
Early Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico
During the 2010 dengue–leptospirosis epidemic in Puerto Rico, enhanced surveillance identified leptospirosis cases and, through a case–control analysis, found that early laboratory abnormalities (low bicarbonate with high creatinine, high white blood cell count, and low platelet…
DOI: 10.1371/journal.pntd.0004482 -
Emerging wildlife diseases – impact on trade, human health and the environment
Emerging wildlife diseases threaten trade, human health, and ecosystems, underscoring the need for enhanced wildlife health surveillance networks and cross-sector collaboration.
DOI: 10.1071/ma05053 -
A pilot study of elevated abortion and stillbirth ratios in cattle in the foothills of the Eastern plains of Colombia
A pilot case-control study on nine cattle farms in the Eastern plains of Colombia investigates elevated abortion/stillbirth ratios, identifying higher Leptospira hardjo seroprevalence (and lower Chlamydia psittaci seroprevalence) on case farms, suggesting leptospirosis as a pote…
DOI: 10.1016/0167-5877(94)00394-x -
Outbreak of Leptospirosis among Triathlon Participants and Community Residents in Springfield, Illinois, 1998
An investigation of a leptospirosis outbreak in Springfield, Illinois (1998) linked to lake water exposure during a triathlon, showing a high attack rate among athletes and substantial community cases after heavy rainfall, with laboratory confirmation and environmental/animal te…
DOI: 10.1086/340615 -
Urban epidemic of severe leptospirosis in Brazil
Active hospital-based surveillance in Salvador, Brazil (March–November 1996) identified an urban epidemic of severe leptospirosis (326 cases; 50 deaths; CFR 15%), linked disease predominantly to Leptospira interrogans serogroup Icterohaemorragghiae with serovar Copenhageni, high…
DOI: 10.1016/s0140-6736(99)80012-9 -
Preparation and standardization of Human papillomavirus (HPV) (Genotype 6) Nosode
This study details the preparation and standardization of a homeopathic nosode derived from Human papillomavirus (HPV) genotype 6 sourced from genital wart tissues, demonstrating its potential for future therapeutic applications.
DOI: 10.51910/ijhdr.v18i3-4.965 -
Effect of Homeopathic Medicines and a Nosode on Larvae of Cochliomyia hominivorax (Diptera: Calliphoridae)
Homeopathic medicines Sulfur 12cH and Pyrogenium 12cH, plus nosodes prepared from Cochliomyia hominivorax larvae, inhibited third-stage larval development of C. hominivorax in vitro, with mortality rates for the treatments comparable to the organophosphate insecticide trichlorfo…
DOI: meta/10.1055/s-0038-1677479 -
Preparation of Cancer Nosodes from specific cancer tissues
Systematic preparation of cancer nosodes from six histopathologically diagnosed human cancers using traditional homeopathic potentization, documenting sources, potencies, and force parameters for research and potential clinical application.
DOI: 10.51910/ijhdr.v18i1.912 -
An attempt to estimate the noises in Homeopathic Pathogenetic Trials by employing the Jaccard Similarity Index and Noise Index.
Jaccard similarity index and Noise index quantify overlap between placebo symptoms and treatment symptoms in homeopathic pathogenetic trials, revealing measurable overlaps for Plumbum metallicum, Piper methysticum, and Hepatitis C nosode and suggesting these metrics can aid nois…
DOI: 10.51910/ijhdr.v22i2.1327 -
In-Vitro Evaluation of Antimicrobial Activities of Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Neisseria gonorrhoeae, and Candida albicans Nosodes
Potentized nosodes demonstrated in-vitro antimicrobial activity against their corresponding organisms and some cross-activity against related species in MIC assays, indicating potential antimicrobial effects of these homeopathic preparations in vitro.
DOI: 10.1055/s-0041-1727149 -
Everything Comes into Me: Vernix Caseosa
A homeopathic column presenting Vernix caseosa as a remedy for oversensitivity and lack of protective boundaries, illustrated by two patient cases where single or repeated doses led to reported improvements.
DOI: 10.1055/s-0037-1605357 -
Detection of Markers of Cardiovascular and Renal Risk in Cuba: Isle of Youth Study (ISYS)
The Isle of Youth Study (ISYS) reveals a high prevalence of renovascular damage markers and associated risk factors in the adult population of Cuba, highlighting the need for community-based health interventions.
DOI: 10.1159/000321505 -
Development of a mobile application for Early Warning Systems and risk management in Cuba
SATEMovil enables rapid dissemination of early warnings for six threat categories via SMS, MMS, and NAUTA mail, with geographic localization on maps to support Cuban risk management.
DOI: 10.1088/1757-899x/1154/1/012005 -
Effect of age on outcome of secondary dengue 2 infections
This epidemiological study analyzes age-specific mortality and hospitalization rates during secondary dengue virus type 2 infections in Cuba in 1981, showing the highest risk in young children and the elderly compared with adults.
DOI: 10.1016/s1201-9712(02)90072-x -
Polymorphism of KIR Genes in Women with Human Papillomavirus Infection
Screening of 3,115 Cuban women aged 30–50 identified 9.5% high-risk HPV prevalence, and KIR gene typing in 60 HPV-positive women showed high frequencies of activating receptors (KIR2DL1, KIR2DL3, KIR2DS4), suggesting NK cell receptor polymorphisms may influence HPV infection in …
DOI: 10.23880/vij-16000319 -
Humans against Obesity: Who Will Win?
BMI alone is an inadequate measure of obesity-related disease risk, and eradicating obesity will require a global, multisectoral transformation of the obesogenic environment, as illustrated by Cuba's Special Period and the metabolic heterogeneity among high-BMI individuals.
DOI: 10.1093/advances/nmy055 -
Spatial analysis of breast and cervical cancer incidence in small geographical areas in Cuba, 1999–2003
This study analyzes the geographical variation in breast and cervical cancer incidence in Cuba from 1999 to 2003, identifying high-risk areas and supporting the hypothesis of spatial risk variation influenced by lifestyle and socioeconomic factors.
DOI: 10.1097/CEJ.0b013e32832f9b93 -
Development of an active risk-based surveillance strategy for avian influenza in Cuba
This study develops and applies a GIS-based, risk-based surveillance strategy to select high-risk poultry farms for active avian influenza surveillance in western Cuba, identifying 31 farms near migratory waterfowl for targeted sampling and proposing a multi-season approach to e…
DOI: 10.1016/j.prevetmed.2014.05.012 -
Updated distribution and experimental life-history traits of the recently invasive snail Lissachatina fulica in Havana, Cuba
This study updates the distribution and life-history traits of the invasive giant African snail Lissachatina fulica in Havana, Cuba, highlighting its rapid establishment and potential for spread as a vector for parasites.
DOI: 10.1016/j.actatropica.2018.04.019 -
Prevalence of low scores on language tests as a potential factor in misdiagnosis of cognitive impairment in a Spanish-speaking adult population
Large-scale cross-cultural normative data show frequent low scores on language measures (Boston Naming Test and Verbal Fluency) among healthy Spanish-speaking adults across 11 Latin American countries, highlighting the risk of misdiagnosing cognitive impairment and the need for …
DOI: 10.1080/23279095.2019.1704409 -
Relation between serum lipoperoxide concentrations and iron or copper status over one year in Cuban adult men
This study investigates the relationship between serum lipoperoxide concentrations and iron or copper status over one year in healthy middle-aged Cuban men, revealing significant correlations and seasonal variations in lipid peroxidation and metal status.
DOI: 10.1016/s0946-672x(01)80022-5 -
The impact of hurricane strikes on Caribbean sovereign bond returns
This study analyzes how hurricane strikes in the early 20th-century Caribbean affected sovereign bond returns for Cuba, the Dominican Republic, and Haiti, using a hurricane-destruction index within a fixed-effects panel to show a temporary rise in returns (roughly 0.9 percentage…
DOI: 10.1017/s096856502500006x -
Prevalence and Risk of Mild Cognitive Impairment in Low and Middle-Income Countries: A Systematic Review
This is a comprehensive systematic review synthesizing the prevalence and risk factors of mild cognitive impairment (MCI) in low- and middle-income countries (LMICs), highlighting vast heterogeneity driven by differing diagnostic criteria and methodologies, and calling for stand…
DOI: 10.3233/jad-201043