Question explored with the scientific record
What is the risk of SOD from cholasectamy
The short version: the evidence you retrieved does not define "SOD" and does not study sodium nitrite exposure from cholecystectomy, so the question cannot be answered from these records.
The retrieved studies cover complications of gallbladder surgery like bile duct injury, infection, bleeding, and fluid collections [1, 2, 5, 12, 18]. None of them mention sodium nitrite, "SOD," or any chemical exposure from the procedure. One study on nitrate and nitrite toxicity in water fleas [15] and one on water intoxication in pigs [16] are completely off-topic for a human surgical question. The evidence is empty for the specific risk you are asking about.
If "SOD" means something like superoxide dismutase or a specific post-surgical syndrome, the records here do not address it. A cholecystectomy is a common operation with well-documented risks—bile duct injury happens in about 2 in 1,000 cases [18], infection and bleeding in a few percent [5]—but no retrieved study tests whether sodium nitrite or any "SOD"-related outcome follows the surgery. The burden of proof is on whoever claims a specific risk exists, and these records do not meet it.
My call: the evidence does not support any conclusion about SOD risk from cholecystectomy. Confidence: not clear—the retrieval simply does not cover the question.
Sources examined 18
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Investigating the Relationship Between the Monocyte Percentage and Monocyte-Lymphocyte Ratio with the Type, Duration, and Complications of Cholecystectomy: A Cross-sectional Study
This cross-sectional study of 189 cholecystectomy patients evaluates whether monocyte percentage and monocyte-to-lymphocyte ratio (MLR) relate to the type, duration, and postoperative complications of cholecystectomy, finding that higher MLR is associated with certain complicati…
DOI: 10.34172/ddj.1652 -
Endoscopic diagnosis and management of complications following surgery for gallstones
This study reviews the efficacy of endoscopic retrograde cholangiopancreatography (ERCP) in managing postoperative complications following gallstone surgery, analyzing 418 patients and highlighting the success rates and types of complications encountered.
DOI: 10.1007/s00464-002-9048-7 -
The Value of Postoperative Ultrasound Examination After Laparoscopic Laser Cholecystectomy Surgery
This study evaluates the effectiveness of postoperative ultrasound examinations in predicting complications for patients undergoing laparoscopic cholecystectomy, finding that while 25% of patients exhibited small fluid collections post-surgery, these did not correlate with any c…
DOI: 10.1089/lps.1991.1.187 -
Laparoscopic Adrenalectomy Has the Same Operative Risk as Routine Laparoscopic Cholecystectomy
This study compares the safety profiles of laparoscopic adrenalectomy and laparoscopic cholecystectomy, finding that both procedures have similar operative risks despite differences in patient demographics and comorbidities.
DOI: 10.1016/j.jss.2019.03.042 -
A Comparative Study of Postoperative Outcomes: Open Cholecystectomy versus Laparoscopic Cholecystectomy
A prospective randomized study comparing laparoscopic versus open cholecystectomy in 100 patients with symptomatic cholelithiasis, showing laparoscopic cholecystectomy to have shorter operative time, less postoperative pain, shorter hospital stay, and fewer complications than op…
DOI: 10.69750/dmls.01.05.053 -
Corset Trunkplasty: Recommended with Abdominal Skin Laxity and Open Cholecystectomy Scar
This study compares the outcomes of corset trunkplasty and traditional abdominoplasty in patients with previous upper abdominal scars, finding that the corset technique results in fewer postoperative complications.
DOI: 10.1097/PRS.0000000000003988 -
Randomized clinical trial of single-port, minilaparoscopic and conventional laparoscopic cholecystectomy
This randomized clinical trial compared single-port and minilaparoscopic cholecystectomy to conventional laparoscopic cholecystectomy, finding no significant differences in postoperative pain or outcomes, but longer operating times and higher complication rates for the newer tec…
DOI: 10.1002/bjs.9003 -
Transumbilical single-incision laparoscopic cholecystectomy: long-term review from a single center
This study provides a long-term review of 529 patients who underwent transumbilical single-incision laparoscopic cholecystectomy (SILC), highlighting postoperative recovery, complications, and factors influencing recovery outcomes.
DOI: 10.1007/s00464-015-4618-7 -
Laparoscopic Cholecystectomy and Liver Cirrhosis
This study evaluates the safety and efficacy of laparoscopic cholecystectomy in cirrhotic patients, revealing that while the procedure can be performed safely in Child-Pugh class A and B patients, it carries higher risks of complications compared to non-cirrhotic patients.
DOI: 10.1097/SLE.0b013e31823b5096 -
Laparoscopic cholecystectomy in young patients with sickle hemoglobinopathies
This study evaluates the safety and efficacy of laparoscopic cholecystectomy in nine young patients with sickle hemoglobinopathies, reporting no complications and a mean postoperative hospital stay of 1.6 days.
DOI: 10.1016/s0022-3476(05)80598-0 -
Laparoscopic versus open cholecystectomy in diabetic patients and postoperative outcome
This study retrospectively evaluates the postoperative outcomes of laparoscopic versus open cholecystectomy in diabetic patients, finding that laparoscopic surgery is associated with lower complication rates and mortality compared to open surgery.
DOI: 10.1007/s00464-010-1248-y -
The chain of postoperative complications after laparoscopic cholecystectomy
A 50-year-old woman with Strasberg type E2 bile duct injury during laparoscopic cholecystectomy was treated with simultaneous hepaticojejunostomy; an unrecognized aberrant right posterior sectoral duct caused persistent bile leak, and percutaneous drainage catheter migration to …
DOI: 10.5152/ucd.2013.25 -
Clostridium perfringens sepsis and liver abscess following laparoscopic cholecystectomy
A case report of Clostridium perfringens sepsis with a gas-forming liver abscess following laparoscopic cholecystectomy, detailing rapid surgical and medical management that led to survival.
DOI: 10.1093/jscr/2012.1.5 -
Study of laparoscopic cholecystectomy in gallstones induced pancreatitis
Early vs delayed laparoscopic cholecystectomy for gallstone pancreatitis yields similar intraoperative difficulty and postoperative complications, but delaying increases total hospital stay.
DOI: 10.18203/2349-2902.isj20181057 -
Intracellular Conversion of Environmental Nitrate and Nitrite to Nitric Oxide with Resulting Developmental Toxicity to the Crustacean Daphnia magna
The study demonstrates that environmental nitrate and nitrite can be intracellularly converted to nitric oxide in arthropod cells and the whole crustacean Daphnia magna, leading to reproductive and developmental toxicity, with nitrite (NO2−) generally more potent than nitrate (N…
DOI: 10.1371/journal.pone.0012453 -
Sodium ion and water intoxication syndrome in two pet miniature pigs ( Sus scrofa )
Two pet miniature pigs developed sodium/water intoxication after water deprivation, showing neurological signs despite normonatremia in one case, and were successfully treated with conservative therapy and diuretics.
DOI: 10.1136/vetreccr-2014-000142 -
Prognostication of Learning Curve on Surgical Management of Vasculobiliary Injuries after Cholecystectomy
This study evaluates the outcomes of surgical management of iatrogenic bile duct injuries with and without concomitant vascular injuries in a new hepatobiliary center during its learning curve, finding that the learning curve does not negatively impact surgical outcomes.
DOI: 10.1155/2016/2647130 -
Bile duct injuries (BDI) in the advanced laparoscopic cholecystectomy era
This study analyzes data from the National Surgical Quality Improvement Program to assess the incidence of bile duct injuries (BDI) during laparoscopic cholecystectomy, finding a current rate of 0.19%, which is significantly lower than previously reported rates and comparable to…
DOI: 10.1007/s00464-018-6333-7