Question explored with the scientific record
Conversation so far
- 1 If you have hypoventilation due to autonomic neuropathy or blunted chemorecptors what is the best intervention + a private exchange
- 2 Is the link between late diagnosed celiac and autonomic disorders established?
- 3 Is there an established link between celia disease and neuropathy?
- 4 Is the study done in England (sheffield?)using a huge dataset of celiac patients included
- 5 Can you find
Answered on this page ↓
Can you find
The short version: the retrieved evidence does not contain a Sheffield-based large-dataset study of celiac patients and neuropathy, so the specific study you are asking about is not in these records.
The evidence here contains several studies on celiac disease and neuropathy, but none from Sheffield and none using a large dataset. A 2010 study of 274 celiac patients (125 elderly, 149 young adults) found neuropathy in 11% of the elderly and 4% of the young adults [2], but that was a clinical comparison, not a population-level dataset. A 2005 study of 26 well-controlled celiac patients found 23% had peripheral neuropathy on testing [1], but again a small clinical sample.
The retrieval also includes a 2025 study using TCRβ repertoire sequencing from 884 celiac cases and 3,624 controls [3], and a 2025 whole-genome RNA sequencing study of 283 pediatric samples [4], but neither addresses neuropathy at all. A 2008 study on celiac disease and type 1 diabetes mentions peripheral nerve function in its title but the extracted data covers haptoglobin polymorphism, not nerve outcomes [5].
What is missing: any population-level study from Sheffield, any UK-based large dataset on celiac patients, and any study that systematically measures neuropathy rates across a large celiac cohort. The question of whether a specific Sheffield study found an association with neuropathy cannot be answered from these records.
My call: the evidence here does not contain the study you are asking about. The link between celiac disease and neuropathy is supported by smaller clinical studies [1][2], but no large-dataset Sheffield study is present in this retrieval.
Confidence: high that the specific study is absent from these records.
Sources used 5
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Noninvasive Ventilation in COPD
This study investigates the impact of high-intensity noninvasive positive pressure ventilation (HI-NPPV) compared to low-intensity noninvasive positive pressure ventilation (LI-NPPV) on sleep quality in patients with chronic obstructive pulmonary disease (COPD) and finds no sign…
DOI: 10.1378/chest.11-0253 -
New strategies to improve exercise tolerance in chronic obstructive pulmonary disease
This review synthesizes emerging strategies to enhance exercise tolerance in COPD by enabling higher training intensity through noninvasive ventilatory support, oxygen, electrical stimulation, interval training, and biofeedback, while highlighting benefits, limitations, and the …
DOI: 10.1183/09031936.04.00002904 -
Phrenic nerve pacing in infants and children: A review of experience and report on the usefulness of phrenic nerve stimulation studies
This study reviews the experience and utility of phrenic nerve pacing in infants and children, highlighting the variability in phrenic nerve conduction times and diaphragmatic action potential amplitudes, and demonstrating the effectiveness of this method in providing ventilator…
DOI: 10.1016/s0022-3476(83)80282-0 -
Phrenic Nerve Stimulation (Diaphragm Pacing) in Respiratory Paralysis
Diaphragm pacing via implanted phrenic nerve stimulators allowed 12 of 16 patients with central respiratory insufficiency to become independent of conventional ventilators during follow-up of 5-72 months; two patients died and two had limited benefit.
DOI: 10.1159/000101155 -
‘Hyperacute’ Guillain-Barré Syndrome
"Hyperacute" Guillain-Barré Syndrome: a case-series of five Israeli patients in which nadir of weakness occurred within hours to a day, detailing clinical features, electrophysiology, treatment (plasmapheresis/IVIg), and generally favorable recovery with distal involvement and v…
DOI: 10.1159/000109575